Methylene diphenyl diisocyanate mdi in commercial form typically exists as a mixture of 4,4mdi monomer and certain oligomers of mdi encyclopedia of chemical technology, 1983. Mdi and other isocyanates may also cause hypersensitivity pneumonitis, another allergic lung disease, which is characterized by symptoms such as shortness of breath, fever, tiredness, non productive cough, and chills. Methylene bisphenyl isocyanate has not been tested for its ability to affect reproduction. It is majorly used in the synthesis of polyurethane. Diphenylmethane diisocyanate mdi note that the layout and pagination of this pdf file are not identical to those of the printed cicad first draft prepared by dr j. One of these compounds is 4, 4 methylene diphenyl diisocyanate mdi, which is widely used in the production of rigid polyurethane foams and also used to a lesser extent in coatings, adhesives, sealants, and elastomers. Download msds polymeric mdi silver fern chemical, inc. The commercial form of 4,4methylenediphenyl diisocyanate mdi is used to. The 2016 emergency response guidebook, developed jointly by transport canada tc, the u. Additional precautions may be necessary based on special. Methylene diphenyl diisocyanate monomeric mdi and polymeric. We enable science by offering product choice, services, process excellence and our people make it happen. Diphenylmethane4,4diisocyanate 101688 msds, safety. Risk management for methylene diphenyl diisocyanate.
Division street arlington, tx 76011 apmdi safety data sheet phone 817 6404900. Polymethylene polyphenylene isocyanate polymeric mdi. Toluene diisocyanate and methylenediphenyl diisocyanate. Other longterm effects methylene bisphenyl isocyanate may cause a skin allergy. Risk management for methylene diphenyl diisocyanate mdi.
Cdc niosh pocket guide to chemical hazards methylene. Both epa and the manufacturers of mdi recognized that early nti estimates of mdi emissions. It is produced, distributed, stored, and consumed in closed systems. Learn more about methylenediphenyl4,4 diisocyanate. If in a solution it may or may not burn depending on the nature of the material andor the solvent. Guidelines for transloading polymeric methylene diphenyl diisocyanate pmdi specific transloading location within the facility to employees who are trained and qualified to participate in the transfer operation. The following fact sheets cover isocyanate compounds. Diphenylmethane 4,4 diisocyanate is a light yellow colored solid. Lot and batch numbers can be found on a products label following the words lot or batch. Basf will proceed with the second phase of its production expansion for methylene diphenyl diisocyanate mdi at its louisiana chemical complex in geismar. Division street arlington, tx 76011 a pmdi safety data sheet. Safety eyewear such as chemical safety goggles or 8 face shield should be used when there is a greater risk of liquid splash. The global market for diisocyanates in the year 2000 was 4.
Methylene bisphenyl isocyanate may cause an asthmalike allergy. Developing a national emissions inventory for 4, 4. Other companies are charging thousands of dollars to set up accounts and. Contact lenses should not be worn when working with this chemical. Polyurethanes pu are polymers made with diisocyanates such as mdi 4,4methylene diphenyl diisocyanate and tdi 2,4toluene diisocyanate and 2,6toluene diisocyanate. Uses include uv curable and latent catalystcontaining polymerization compositions. Isocyanates occupational safety and health administration.
It is unlikely that consumers would be exposed to diisocyanates from cured products, such as cushions. Exposure to these chemicals can affect the respiratory function. Mdi is the standard abbreviation for methylene diphenyl diisocyanate. Sekizawa, national institute of health sciences, japan, in collaboration with dr m. Explore information about air pollutants, contaminants and studies being done. Diphenylmethane diisocyanate, isomers and homologues. Methylenediphenyldiisocyanate mdi 4 6 101688 osha hazardous components 29 cfr 1910. Methylene diphenyl diisocyanate cas 101688 3 not classifiable as to carcinogenicity to humans. Exposure to toluene diisocyanate and methylenediphenyl diisocyanate can occur by contact with uncured polyurethane products.
Sds of 4,4diphenylmethane diisocyanate, safety data. Basf expects to double its production of mdi from 300,000 metric tons to around 600,000 metric tons through the multiphase expansion project announced in january 2018. Diphenylmethane4,4diisocyanate is a light yellow colored solid. Diphenylmethane4,4diisocyanate is a diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4 and 4positions. The main sources of information for this fact sheet are epas. Diphenylmethane4, 4diisocyanate 101688 msds report, diphenylmethane4, 4diisocyanate msds safety technical specifications search, diphenylmethane4, 4diisocyanate safety information specifications ect. Find msds or sds, a coa, data sheets and more information.
The 4,4 isomer is most widely used, and is also known as 4,4diphenylmethane diisocyanate. This method is not inclusive with respect to specifications e. Mdi refers to a mixture of 4,4 methylenediphenyl diisocyanate and its isomers. Methylene diphenyl diisocyanate mdi and related compounds.
Exposure to toluene diisocyanate tdi and methylenediphenyl diisocyanate mdi can occur from inhaling air where uncured unreacted products such as adhesives, sealants, coatings, paints, craft materials, and insulating foams are present. Toluene diisocyanate and methylendiphenyl diisocyanatetoxfaqs. Chemical name isocyanic acid, polymethylene polyphenylene ester. However, a number of states have incorporated provisions of the 1989 standard in their state plans. Download the complete methylene diphenyl diisocyanate mdi action plan pdf access the public comment docket for the methylene diphenyl diisocyanate mdi action plan docket id epahqoppt20110182 on regulations. Sds of 4,4diphenylmethane diisocyanate, safety data sheets. Product safety assessment dow modified methyl diphenyl. Product safety assessment mdibased isocyanate products. Msds for invisalign appliance materials ex15, ex30.
Product and company identification isocyanate mdii a component. Methylene diphenyl diisocyanate diphenylmethane diisocyanate methylene bispphenyl isocyanate methylene bisphenyl isocyanate 1,1. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. The intention was to update information to incorporate the changes to the mutual aid emergency response scheme as agreed between the. Diphenylmethane4,4 diisocyanate is a light yellow colored solid. Exposure to the spilled material may be irritating or harmful. Commercial tdi is marketed as a mixture of the 2,4 and 2,6 isomers, predominantly at a ratio of 80. Methylene diphenyl diisocyanate, most often abbreviated as mdi, is an aromatic di isocyanate. August 21, 2015 the dow chemical company page 2 of 8 is used as a raw material to make materials that consumers purchase. Polymethylene polyphenyl isocyanate cas 9016879 3 not classifiable as to carcinogenicity to humans. Mdi screening procedure page 1 of 7 screening method for methylene diphenyl diisocyanate mdi note.
Additionally, osha has announced that it may cite companies under the. Follow personal protective equipment recommendations found in section 8 of this msds. Investigations have been undertaken with mdi and tdi to assess dermal uptake and resulting systemic exposure. Methylenebis cyclohe xyl isocyanate, mixture of isomers hmdi is an aromatic diisocyanate with good mechanical properties.
Responsibilities for hazmat employees may include, but are not limited to, the following. Some material is incorporated by reference from other epa methods. New jersey department of health and senior services. Polymethylene polyphenyl isocyanate cas 9016879 3 not. Use of an impingerfilter sampling technique enables sampling of the mdi monomers and oligomers in vapor and. Material safety data sheet isocyanate mdii a component revised date. Roofers and insulation workers can be exposed to mdi by breathing it in, through skin contact, and by touching things that go into their mouths, like cigarettes or food. The content of monomeric mdi generally is between 45% and 65% on a ww basis mobay, 1983. Includes detailed reports on specific chemicals, covering hazard summaries, identification, exposure routes, health hazards, and ways of reducing exposure. This action plan addresses the use of methylene diphenyl diisocyanate mdi and related compounds see appendix 1 in products that may result in consumer and general population. Three isomers are common, varying by the positions of the isocyanate groups around the rings. Guidance for medical personnel foreward this guidance document is designed specifically for medical personnel to provide current information about the potential health effects from diisocyanate 1 exposure, and to provide guidance to assist with medical diagnosis and management. Opisocyanatobenzylphenyl isocyanate cas 5873541 3 not classifiable as to carcinogenicity to humans. Methylenebiscyclohexyl isocyanate, mixture of isomers.
A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. Guidelines for transloading polymeric methylene diphenyl. Diphenylmethane4,4diisocyanate cameo chemicals noaa. A monofunctional isocyanate of industrial significance is methyl isocyanate mic, which. Substitution preformed rather than spray foam insulation can. Dow modified methylene diphenyl diisocyanate mdi products revised. This action plan addresses the use of methylene diphenyl diisocyanate mdi and related compounds see appendix 1 in products that may result in consumer and general population exposures, particularly in or around buildings, including homes and schools. Polyurethane from methylene diphenyl diisocyanate and 1, 6hexanediol. Cover exposed skin area with appropriate clothing to prevent skin contact.
It may be toxic by ingestion, inhalation, or skin absorption. If allergy develops, very low future exposure can cause itching and a skin rash. Methylene diphenyl diisocyanate diphenylmethane diisocyanate methylene bis pphenyl isocyanate methylene bisphenyl isocyanate 1,1. Msds for invisalign appliance materials ex15, ex30, and ex40. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. This iris assessment for methylene diphenyl diisocyanate monomeric mdi and polymeric mdi pmdi consists of hazard identification and doseresponse assessment data and provides support for epa risk management decisions.
Hmdi forms nco linkages which can be used in the synthesis of polyurethanes for a variety of biomedical. Diphenylmethane 4, 4diisocyanate mixture of diand triisocyanates for synthesis. Guidance for medical personnel foreward this guidance document is designed specifically for medical personnel to provide current information about the potential health effects from diisocyanate 1 exposure, and to provide guidance to. Page 1 of 10 safety data sheet toluene diisocyanate. Toluene diisocyanate and methylendiphenyl diisocyanate.
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